Pombo Lab

Epigenetic regulation
and chromatin architecture

Our group is interested in understanding the interplay between gene regulation and genome architecture, towards defining rules and principles of genome function.

Professor Portrait

Selected Publications

Haplotype-resolved genome architecture mapping uncovers pervasive structural heterogeneity between human homologous chromosomes
Kukalev A Markowski J
bioRxiv , 2026
Specialised super-enhancer networks in stem cells and neurons.
Speakman L Harabula I
bioRxiv , 2026
Extensive folding variability between homologous chromosomes in mammalian cells.
Kukalev A Irastorza-Azcarate I
Mol Syst Biol , 2025
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